The woman, a Poughkeepsie resident, was hit around 9:48 a.m. at the intersection of Church Street and Jefferson Street by a motor vehicle, which fled the scene, said Capt. Richard T. Wilson.
The bicyclist was transported to a local hospital with serious but non-life threatening injuries, he added.
The vehicle, which left the scene of the accident, is described as a dark colored. The vehicle fled eastbound on Church Street immediately following the crash, Wilson said.
Anyone who may have witnessed the crash or has any information is asked to contact the City of Poughkeepsie Police Department Tips Line at 845-451-7577 or City of Poughkeepsie Traffic at 845-451-4131.
To follow @DVDutchess, Daily Voice Dutchess on Twitter, click here.
To follow @PutnamDV, Putnam Daily Voice on Twitter, click here.
Click here to follow Daily Voice Poughkeepsie and receive free news updates.